Yes, an AD connection be able to handle multiple SSL certificates.
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Yes, below sample for reference:
You can configure a high-availability connection to Active Directory. To support high-availability, the connector uses the domain controller (DC) locator process to locate an active domain controller. To leverage static domain controller locater feature, specify URLs of domain controllers as comma-separated values in the URL connection parameter of EIC. If the first DC is not active, EIC checks for the next available DC in the list. If the DC is active, EIC uses it for connecting to Active Directory. For more information, see DC Locator.